The invention of antibiotics is a great achievement for the human race. We have suffered a lot from many known unknown diseases, where the invention of antibiotics has brought a revolution. In this article, I am going to talk about Invention of Antibiotics. You may also love to know about when was the wheel invented.
In this list of invention of Antibiotics, I have shared the timeline of modern antimicrobial (anti-infective) therapy, useful for particular diseases, symptoms, and signs. In this list, you will also find the years when a mentioned drug was publicly released onto the pharmaceutical market for general uses recommend by the authorized physicians. We have eliminated the timeline of the development of the antibiotics themselves in the following list.
Invention of Antibiotics – A List
- 1911 – Arsphenamine a.k.a. Salvarsan
- 1912 – Neosalvarsan
- 1935 – Prontosil (an oral precursor to sulfanilamide), the first sulfonamide
- 1936 – Sulfanilamide
- 1938 – Sulfapyridine (M&B 693)
- 1939 – sulfacetamide
- 1940 – sulfamethizole
- 1942 – benzylpenicillin, the first penicillin
- 1942 – gramicidin S, the first peptide antibiotic
- 1942 – sulfadimidine
- 1943 – sulfamerazine
- 1944 – streptomycin, the first aminoglycoside[2]
- 1947 – sulfadiazine
- 1948 – chlortetracycline, the first tetracycline
- 1949 – chloramphenicol, the first amphenicol[2]
- 1949 – neomycin
- 1950 – oxytetracycline
- 1950 – penicillin G procaine
- 1952 – erythromycin, the first macrolide[2]
- 1954 – benzathine penicillin
- 1955 – spiramycin
- 1955 – tetracycline
- 1955 – thiamphenicol
- 1955 – vancomycin, the first glycopeptide
- 1956 – phenoxymethylpenicillin
- 1958 – colistin, the first polymyxin
- 1958 – demeclocycline
- 1959 – virginiamycin
- 1960 – methicillin
- 1960 – metronidazole, the first nitroimidazole
- 1961 – ampicillin
- 1961 – spectinomycin
- 1961 – sulfamethoxazole
- 1961 – trimethoprim, the first dihydrofolate reductase inhibitor
- 1962 – cloxacillin
- 1962 – fusidic acid
- 1963 – fusafungine
- 1963 – lymecycline
- 1964 – gentamicin
- 1964 – cefalotin, the first cephalosporin
- 1966 – doxycycline
- 1967 – carbenicillin
- 1967 – rifampicin
- 1967 – nalidixic acid, the first quinolone
- 1968 – clindamycin, the second lincosamide
- 1970 – cefalexin
- 1971 – cefazolin
- 1971 – pivampicillin
- 1971 – tinidazole
- 1972 – amoxicillin
- 1972 – cefradine
- 1972 – minocycline
- 1972 – pristinamycin
- 1973 – fosfomycin
- 1974 – talampicillin
- 1975 – tobramycin
- 1975 – bacampicillin
- 1975 – ticarcillin
- 1976 – amikacin
- 1977 – azlocillin
- 1977 – cefadroxil
- 1977 – cefamandole
- 1977 – cefoxitin
- 1977 – cefuroxime
- 1977 – mezlocillin
- 1977 – pivmecillinam
- 1979 – cefaclor
- 1980 – cefmetazole
- 1980 – cefotaxime
- 1980 – piperacillin
- 1981 – co-amoxiclav (amoxicillin/clavulanic acid)
- 1981 – cefoperazone
- 1981 – cefotiam
- 1981 – cefsulodin
- 1981 – latamoxef
- 1981 – netilmicin
- 1982 – ceftriaxone
- 1982 – micronomicin
- 1983 – cefmenoxime
- 1983 – ceftazidime
- 1983 – ceftizoxime
- 1983 – norfloxacin
- 1984 – cefonicid
- 1984 – cefotetan
- 1984 – temocillin
- 1985 – cefpiramide
- 1985 – imipenem/cilastatin, the first carbapenem
- 1985 – ofloxacin
- 1986 – mupirocin
- 1986 – aztreonam
- 1986 – cefoperazone/sulbactam
- 1986 – co-ticarclav (ticarcillin/clavulanic acid)
- 1987 – ampicillin/sulbactam
- 1987 – cefixime
- 1987 – roxithromycin
- 1987 – sultamicillin
- 1987 – ciprofloxacin, the first 2nd-gen fluoroquinolone
- 1987 – rifaximin, the first ansamycin
- 1988 – azithromycin
- 1988 – flomoxef
- 1988 – isepamycin
- 1988 – midecamycin
- 1988 – rifapentine
- 1988 – teicoplanin
- 1989 – cefpodoxime
- 1989 – enrofloxacin
- 1989 – lomefloxacin
- 1989 – moxifloxacin
- 1990 – arbekacin
- 1990 – cefodizime
- 1990 – clarithromycin
- 1991 – cefdinir
- 1992 – cefetamet
- 1992 – cefpirome
- 1992 – cefprozil
- 1992 – ceftibuten
- 1992 – fleroxacin
- 1992 – loracarbef
- 1992 – piperacillin/tazobactam
- 1992 – rufloxacin
- 1993 – brodimoprim
- 1993 – dirithromycin
- 1993 – levofloxacin
- 1993 – nadifloxacin
- 1993 – panipenem/betamipron
- 1993 – sparfloxacin
- 1994 – cefepime
- 1996 – meropenem
- 1999 – quinupristin/dalfopristin
- 2000 – linezolid, the first oxazolidinone
- 2001 – telithromycin, the first ketolide
- 2003 – daptomycin
- 2005 – tigecycline, the first glycylcycline
- 2005 – doripenem
- 2009 – telavancin, the first Lipoglycopeptide
- 2010 – ceftaroline
- 2011 – fidaxomicin
- 2012 – bedaquiline
- 2013 – telavancin
- 2014 – tedizolid
- 2014 – dalbavancin
- 2014 – ceftolozane/tazobactam
- 2015 – ceftazidime/avibactam
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