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Invention of Vaccines – TimeLine | History | Inventors

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(Last Updated On: April 16, 2021)

Earlier, it was very risky and hazardous to survive in some particular medical complications. The invention of vaccines has brought a revolution in human civilization. The chronology of the invention of vaccines is too long, started in the 18th century. In this article, I am going to give an overview of the invention of vaccines.

You may also love to know about the invention of antibiotics.

Invention of vaccines

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Let’s find below the timeline of the invention of vaccines:

18th century invention of vaccines

  • 1796 Edward Jenner develops and documents the first vaccine for smallpox.

19th century invention of vaccines

  • 1880 First vaccine for cholera by Louis Pasteur
  • 1885 First vaccine for rabies by Louis Pasteur and Émile Roux
  • 1890 First vaccine for tetanus (serum antitoxin) by Emil von Behring
  • 1896 First vaccine for typhoid fever by Almroth Edward Wright, Richard Pfeiffer, and Wilhelm Kolle
  • 1897 First vaccine for bubonic plague by Waldemar Haffkine

20th century invention of vaccines

  • 1921 First vaccine for tuberculosis by Albert Calmette
  • 1923 First vaccine for diphtheria by Emil von Behring and Kitasato Shibasaburō
  • 1924 First vaccine for scarlet fever by George F. Dick and Gladys Dick
  • 1924 First inactive vaccine for tetanus (tetanus toxoid, TT) by P. Descombey
  • 1926 First vaccine for pertussis (whooping cough) by Leila Denmark
  • 1932 First vaccine for yellow fever by Max Theiler
  • 1937 First vaccine for typhus by Rudolf Weigl, Ludwik Fleck, and Hans Zinsser
  • 1937 First vaccine for influenza by Anatol Smorodintsev
  • 1941 First vaccine for tick-borne encephalitis
  • 1952 First vaccine for polio (Salk vaccine)
  • 1954 First vaccine for Japanese encephalitis
  • 1954 First vaccine for anthrax
  • 1957 First vaccine for adenovirus-4 and 7
  • 1962 First oral polio vaccine (Sabin vaccine)
  • 1963 First vaccine for measles
  • 1967 First vaccine for mumps
  • 1970 First vaccine for rubella
  • 1977 First vaccine for pneumonia (Streptococcus pneumoniae)
  • 1978 First vaccine for meningitis (Neisseria meningitidis)
  • 1980 Smallpox declared eradicated worldwide due to vaccination efforts
  • 1981 First vaccine for hepatitis B (first vaccine to target a cause of cancer)
  • 1984 First vaccine for chicken pox
  • 1985 First vaccine for Haemophilus influenzae type b (HiB)
  • 1989 First vaccine for Q fever
  • 1991 First vaccine for hepatitis A
  • 1998 First vaccine for Lyme disease
  • 1998 First vaccine for rotavirus

21st century invention of vaccines

  • 2003 First nasal influenza vaccine approved in the U.S. (FluMist)
  • 2006 First vaccine for human papillomavirus (which is a cause of cervical cancer)
  • 2012 First vaccine for hepatitis E
  • 2012 First quadrivalent (4-strain) influenza vaccine
  • 2015 First vaccine for enterovirus 71, one cause of hand foot mouth disease
  • 2015 First vaccine for malaria
  • 2015 First vaccine for dengue fever.
  • 2019 First vaccine for ebola approved.
  • 2020 Vaccine of COVID 19 is on the way, research is ongoing.

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